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Cymbalta & Weight Gain: The Truth Behind The Connection

Cymbalta & Weight Gain: The Truth Behind The Connection
Cymbalta 60 mg 28 St
Cymbalta 60 mg 28 St from


When Cymbalta was first introduced in 2004, it was hailed as a miracle drug for treating depression and anxiety. However, over the years, studies have shown that one of the potential side effects of this medication is weight gain. In this article, we will explore the connection between Cymbalta and weight gain, and what you can do to mitigate this side effect.

What is Cymbalta?

Cymbalta is the brand name for duloxetine, a medication used to treat major depressive disorder, anxiety disorder, and chronic pain. It works by balancing the levels of certain chemicals in the brain, which can improve mood, energy levels, and overall well-being.

How Does Cymbalta Cause Weight Gain?

While the exact mechanism behind Cymbalta-related weight gain is unknown, it is believed to be related to the medication’s effect on appetite and metabolism. Cymbalta can decrease feelings of fullness and increase cravings for high-calorie foods, leading to overeating and weight gain. Additionally, the medication can slow down metabolism, making it harder for the body to burn calories efficiently.

What are the Risks of Weight Gain?

Weight gain is not only a cosmetic concern, but it can also increase the risk of other health problems such as diabetes, high blood pressure, and heart disease. It can also worsen depression and anxiety, as well as lower self-esteem and confidence.

How Can You Manage Weight Gain While Taking Cymbalta?

If you are taking Cymbalta and are concerned about weight gain, there are several strategies you can try:

1. Maintain a Healthy Diet

Eating a balanced diet that is high in fruits, vegetables, whole grains, and lean protein can help you feel full and satisfied while providing your body with the nutrients it needs. Avoiding sugary and high-fat foods can also help you manage your weight.

2. Exercise Regularly

Regular physical activity can help you burn calories and improve metabolism. Try to aim for at least 30 minutes of moderate-intensity exercise, such as brisk walking or cycling, each day.

3. Talk to Your Doctor

If you are experiencing significant weight gain while taking Cymbalta, talk to your doctor. They may be able to adjust your dosage or switch you to a different medication that does not cause weight gain.

4. Monitor Your Weight

Weigh yourself regularly and keep track of any changes. This can help you identify if you are gaining weight and take action to manage it.

5. Seek Support

Joining a support group or talking to a therapist can help you cope with any emotional issues related to weight gain and provide you with strategies for managing it.


While weight gain is a potential side effect of Cymbalta, there are several strategies you can try to manage it. By maintaining a healthy diet, exercising regularly, talking to your doctor, monitoring your weight, and seeking support, you can reduce your risk of weight gain and its associated health problems.

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