Zofran is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It is also used to prevent nausea and vomiting associated with pregnancy. However, many people are unsure about the duration of its effects. In this article, we will discuss how long does Zofran last.
What is Zofran?
Ondansetron, commercially sold as Zofran, is a medication that belongs to the class of serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin in the body, which is responsible for triggering nausea and vomiting. Zofran is available as a tablet, orally disintegrating tablet, and injection.
The half-life of a medication refers to the amount of time it takes for half of the drug to be eliminated from the body. The half-life of Zofran is approximately 3 hours. This means that after 3 hours, half of the drug will be eliminated from your body.
Duration of Action
The duration of action of Zofran varies depending on the dosage and route of administration. The oral tablet form of Zofran starts working within 30 minutes of ingestion and lasts for about 4 to 6 hours. The orally disintegrating tablet form of Zofran also starts working within 30 minutes but lasts for about 4 hours.
The intravenous (IV) injection form of Zofran starts working immediately and lasts for about 4 to 6 hours. The duration of action of Zofran injection can be extended by administering a second dose 4 hours after the first dose.
Zofran and Pregnancy
Zofran is commonly used to treat nausea and vomiting during pregnancy. The duration of action of Zofran in pregnant women is similar to that of non-pregnant individuals. However, it is essential to consult with a healthcare provider before taking any medication during pregnancy.
The dosage of Zofran varies depending on the condition being treated and the age of the patient. The recommended dosage for adults is 8mg taken every 8 hours, with a maximum daily dose of 32mg. The recommended dosage for children is based on their weight and age.
Zofran Side Effects
Like any medication, Zofran can cause side effects. The most common side effects of Zofran include headache, constipation, and diarrhea. More severe side effects, such as allergic reactions, irregular heartbeat, and seizures, are rare but can occur.
Zofran and Drug Interactions
Zofran can interact with other medications, such as tramadol, fentanyl, and phenytoin, increasing the risk of side effects. It is essential to inform your healthcare provider about all the medications you are taking before starting Zofran.
Taking too much Zofran can lead to an overdose, which can cause severe side effects. The symptoms of Zofran overdose include blurred vision, trouble breathing, and seizures. If you suspect an overdose, seek medical attention immediately.
Zofran is a widely used medication to prevent nausea and vomiting caused by various conditions. The duration of action of Zofran varies depending on the dosage and route of administration. The half-life of Zofran is approximately 3 hours, and the medication is generally safe when taken as prescribed. However, it is crucial to consult with a healthcare provider before taking any medication to ensure its safety and effectiveness.